Supplement Safety

Are Supplements Regulated? Quality, Safety & Third-Party Testing

How U.S. supplement law actually works — and how to verify quality for yourself

Can You Take Too Many Supplements? Upper Limits & Toxicity

More is not safer — know the ceilings, watch for overlap, and total up everything you take.

Electrolytes Explained: Sodium, Potassium, Magnesium & More

What electrolytes actually do, when you truly need to supplement, and the kidney and heart cautions to take seriously.

Supplement & Medication Interactions

Find out which supplements are safe to take with your medications and which ones you should avoid. Each guide is based on clinical evidence and …

Supplements to Take (and Avoid) with Adderall

Overview

Adderall (mixed amphetamine salts) and similar ADHD stimulant medications (Vyvanse, Ritalin, Concerta, Dexedrine) work by increasing dopamine …

Supplements to Take (and Avoid) with Antibiotics

Overview

Antibiotics encompass many drug classes including penicillins (amoxicillin), cephalosporins (cephalexin), fluoroquinolones (ciprofloxacin, …

Supplements to Take (and Avoid) with Benzodiazepines

Overview

Benzodiazepines including alprazolam (Xanax), diazepam (Valium), clonazepam (Klonopin), lorazepam (Ativan), and temazepam (Restoril) are …

Supplements to Take (and Avoid) with Beta-Blockers

Overview

Beta-blockers including metoprolol (Lopressor, Toprol-XL), atenolol (Tenormin), propranolol (Inderal), carvedilol (Coreg), and bisoprolol …

Supplements to Take (and Avoid) with Birth Control

Overview

Oral contraceptives (birth control pills) containing synthetic estrogen and progestin are used by over 150 million women worldwide. While …

Supplements to Take (and Avoid) with Blood Pressure Medications

Overview

Blood pressure medications encompass several drug classes including ACE inhibitors (lisinopril, enalapril), ARBs (losartan, valsartan), …

Supplements to Take (and Avoid) with Levothyroxine

Overview

Levothyroxine (brand names: Synthroid, Levoxyl, Tirosint, Euthyrox) is the most prescribed medication in the United States, used by over 20 …

Supplements to Take (and Avoid) with Metformin

Overview

Metformin is the most widely prescribed medication for type 2 diabetes, used by over 120 million people worldwide. It works by reducing …

Supplements to Take (and Avoid) with NSAIDs

Overview

NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) including ibuprofen (Advil, Motrin), naproxen (Aleve), diclofenac, and celecoxib (Celebrex) …

Supplements to Take (and Avoid) with PPIs

Overview

Proton Pump Inhibitors (PPIs) including omeprazole (Prilosec), pantoprazole (Protonix), esomeprazole (Nexium), and lansoprazole (Prevacid) …

Supplements to Take (and Avoid) with SSRIs

Overview

SSRIs (Selective Serotonin Reuptake Inhibitors) like Lexapro (escitalopram), Zoloft (sertraline), Prozac (fluoxetine), and Paxil (paroxetine) …

Supplements to Take (and Avoid) with Statins

Overview

Statins — including atorvastatin (Lipitor), rosuvastatin (Crestor), simvastatin (Zocor), and pravastatin (Pravachol) — are the most …

Supplements to Take (and Avoid) with Steroids (Prednisone)

Overview

Corticosteroids including prednisone, prednisolone, methylprednisolone, and dexamethasone are prescribed for a wide range of conditions: …

Supplements to Take (and Avoid) with Thyroid Medications

Overview

Thyroid medications — including levothyroxine (Synthroid, Levoxyl), liothyronine (Cytomel), and natural desiccated thyroid (Armour Thyroid) — …

Supplements to Take (and Avoid) with Warfarin

Overview

Warfarin (Coumadin) is an anticoagulant (blood thinner) prescribed to prevent blood clots, stroke, and pulmonary embolism. It works by …

Spring-Cleaning Your Supplement Cabinet: What to Toss, What to Keep

Open the cabinet, take everything out, and be honest about what's in there.