Mood

Supplements

Saffron

Standardized saffron extract for mood, mild low mood, and appetite — antidepressant-comparable in small trials, but an adjunct only

Supplements

SAM-e (S-Adenosylmethionine)

A methylation compound with evidence for mood, joint comfort, and liver health — but serious antidepressant interactions

Supplements

St. John's Wort

An evidence-backed mood herb with serious drug interactions — caveats first, always

Supplements

Pregnenolone

The 'grandmother hormone' for cognition, mood, and steroid balance

Supplements

L-Tryptophan

Essential amino acid and serotonin precursor for mood, sleep, and immune support

Supplements

Phosphatidylserine

Neuronal membrane phospholipid for memory, aging, stress resilience, and BDNF support

Supplements

Omega-3 Fish Oil

Essential fats for brain, heart, and whole-body health

Supplements

Vitamin D3

The sunshine vitamin essential for immunity, bones, and mood