Supplements
Methylfolate (5-MTHF, Active Folate)
The active, body-ready form of folate that skips the MTHFR bottleneck
Methylation
Supplements
SAM-e (S-Adenosylmethionine)
A methylation compound with evidence for mood, joint comfort, and liver health — but serious antidepressant interactions
Supplements
TMG/Betaine (Trimethylglycine)
The methyl donor that supports cardiovascular health, detoxification, and cellular energy production
Supplements
Vitamin B12 (Cobalamin)
The methylation and energy cofactor for neurological function, DNA synthesis, and red blood cells
Supplements
Vitamin B9 (Folate)
The one-carbon metabolism cofactor for DNA synthesis, methylation, and neurological health