Research Brief · April 18, 2023

Beetroot, Nitrates, and Blood Pressure: What the Research Shows

A vegetable juice with a real — if modest and short-lived — cardiovascular signal.

Beetroot is an unusual supplement: a deep-red vegetable juice that ended up with a respectable pile of human trials behind it. It gets sold for two main things — supporting healthy blood pressure and boosting endurance — and unlike a lot of the supplement aisle, both claims have real research underneath. The catch is that the effects are smaller, shorter-lived, and more specific than the marketing suggests.

Here’s the honest accounting of what beetroot does, why, and how to use it without overselling it to yourself.

What’s Actually Doing the Work

The headline ingredient in beetroot isn’t some exotic antioxidant — it’s dietary nitrate, the same nitrate found abundantly in leafy greens like spinach, arugula, and chard. Beets just happen to be a convenient, concentrated, palatable source.

The pathway goes like this: you swallow nitrate, bacteria on your tongue convert some of it to nitrite, and your body then converts nitrite to nitric oxide — a signaling molecule that relaxes and widens blood vessels. Wider, more relaxed vessels mean blood flows with slightly less resistance, which is the mechanism behind both the blood-pressure and the exercise effects. If you want the deeper mechanism, our guide to boosting nitric oxide naturally walks through the whole pathway.

One practical implication of that pathway: strong antiseptic mouthwash can blunt beetroot’s effect by killing the tongue bacteria that start the conversion. It’s a small detail that tells you the mechanism is real.

The Blood-Pressure Evidence, Honestly Read

This is beetroot’s most-studied claim, and the evidence is reasonably consistent for a supplement: pooled analyses of controlled trials show that a nitrate-rich beetroot dose produces a small reduction in systolic blood pressure, on the order of 3-5 mmHg, with a smaller effect on diastolic.

Reading that responsibly:

  • The effect is small and temporary. It peaks a couple of hours after a dose and fades — this is a short-term physiological nudge, not a permanent reset. Some studies of daily use over weeks show a sustained modest effect, but it’s still modest.
  • It’s most noticeable in people with higher starting blood pressure. People who are already in a healthy range tend to see less change, which is unsurprising.
  • It is support, not treatment. A few mmHg is a meaningful population-level number, but beetroot is not a substitute for prescribed blood-pressure management, and no one should treat it as one. If blood pressure is a medical concern, that’s a conversation with a clinician.

So the accurate framing: beetroot can support healthy blood pressure modestly and temporarily through a well-understood mechanism. That’s a genuinely good result for a vegetable juice — and still a long way from “lowers blood pressure” as a medical claim.

The Endurance Evidence

Beetroot’s other well-studied use is athletic performance, and here the data is arguably its strongest. By improving the efficiency of oxygen use in muscle, nitrate supplementation has shown small but repeatable improvements in:

  • Exercise economy (using slightly less oxygen at a given effort),
  • Time-to-exhaustion and time-trial performance, especially in endurance efforts.

The effects are most reliable in recreational and sub-elite athletes; highly trained elites — who already have very efficient nitric-oxide systems — tend to respond less. The benefit also shows up best for sustained aerobic work rather than single all-out sprints. It’s a few percent, not a transformation, but in endurance sport a few percent is worth having. People often stack it conceptually with citrulline, which supports nitric oxide by a different route.

Sensible Dosing and Timing

The dose that matters is the nitrate content, not the volume of juice:

  • Effective research doses sit around 300-600 mg of nitrate (often expressed as ~6-8 mmol) — roughly what’s in one concentrated “beet shot” or a couple of cups of beetroot juice.
  • Timing: take it 2-3 hours before you want the effect (a workout, or simply when you want the blood-pressure nudge), since nitric-oxide production peaks in that window.
  • Consistency: for blood-pressure support, daily use is more sensible than occasional; for performance, some people load for a few days before an event.

Concentrated shots and standardized powders make dosing more predictable than whole beets, where nitrate content varies with the soil and growing conditions. See the beetroot supplement page for forms and what to look for, and our heart-health supplements roundup for where beetroot fits among better-evidenced options.

Safety and Quirks

Beetroot is food, and it’s well-tolerated, but a few things are worth knowing:

  • Beeturia and pink stool are normal. Many people pass pink or reddish urine and stool after beets. It’s harmless pigment, not blood — though if you’re ever unsure whether it’s actually blood, that’s worth a medical check.
  • Additive blood-pressure lowering is the real caution. Because beetroot lowers blood pressure, it can stack with blood-pressure medications, nitrate drugs used for chest pain, and erectile-dysfunction medications — all of which also lower blood pressure — potentially dropping it too far. If you take any of these, talk to your prescriber before using beetroot regularly.
  • Kidney stones: beets are relatively high in oxalate, so people prone to calcium-oxalate stones may want to be moderate.
  • Pregnancy and nursing: beetroot as food is fine; concentrated supplemental doses haven’t been well studied, so check with a clinician before using shots or powders routinely.

Bottom Line

Beetroot is one of the more honest products in the supplement aisle: a food-based source of nitrate with a well-understood mechanism and real, if modest, human data. Expect a small, temporary blood-pressure nudge (around 3-5 mmHg systolic) and a few-percent endurance benefit, not a medical-grade effect. It’s a reasonable, low-risk option for endurance support and general cardiovascular curiosity — provided you’re not on blood-pressure or nitrate medications without checking first, and provided you don’t mistake it for treatment.

This article is educational and not medical advice. Supplements aren’t meant to diagnose, treat, cure, or prevent any condition. Talk to a qualified healthcare provider before starting anything new — especially if you’re pregnant, nursing, taking medication, or managing a health condition.